Nowhere on the website does AP state that it's a ladies.
I agree with other comments that for Date Justs and Day Dates - many with large wrists still consider 36mm to be an appropriate size.
The 15450 definitely wears larger due to the integrated bracelet.
At the end of the day - it all comes down to preference! I can say for a fact that up close or far away, the 15450 is a very appropriate size for my 6.3 in. wrist.
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