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When cleaning or merely flushing out a system in prepping for an ink change, make effort to use distilled or deionized water. Though the amount of minerals in most tap water is unlikely to cause problems, the feed mechanisms in our pens are temperamental. With a gallon of distilled water going for perhaps one dollar there are few reasons not to take this minor precaution.
I've read if one periodically uses their pens and there isn't evidence of a clogged feed or, in the event the instrument is a reservoir feed, difficulty in operating the plunger mechanism, there probably isn't cause for concern for 'deep cleaning'. Nearly all mass-produced inks contain some manner of algae/fungus inhibitor and lubricant.
--Robert
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